Under the Project Coordination of EIBIR and the Scientific Coordination of Professor Horst Hahn at Fraunhofer Mevis, Germany, the interdisciplinary consortium of the project proposal “VPH-PRISM: Virtual Physiological Human: Personalized Predictive Breast Cancer Therapy through Integrated Tissue Micro-Structure Modeling” comprises nine partners from Austria, Germany, the Netherlands, the UK and the USA.
Breast cancer is frequent and life threatening, but curable if detected early. Early detection and comprehensive characterisation of findings require optimised imaging and image understanding to maximise detection of significant disease while preventing overdiagnosis. Personalised predictive modelling of breast cancer allows treatment stratification, preventing unnecessary and unsuccessful treatments. VPH-PRISM addresses these key topics with integrated multidisciplinary, multi-scale ICT modelling of breast tissue microstructure in the context of environmental, genetic, and clinical factors.
VPH-PRISM will provide a proof of concept for multidisciplinary model based discovery of environment-tissue interactions, quantitative drug efficacy assessment, surgery planning, and treatment outcome prediction at early and advanced stages of breast cancer.
The project commenced on March 1 2013 and a kick-off meeting was held on March 6 in Vienna, AT.