The “Virtual Physiological Human: DementiA Research Enabled by IT” (VPH-DARE@IT) project aims to provide a systematic, multifactorial and multiscale modelling approach to understanding dementia onset and progression and enable more objective, earlier, predictive and individualised diagnoses and prognoses of dementias to cope with the challenge of an ageing European society.

The number of individuals suffering from dementia today is roughly 36 million and, due to ageing societies, will increase to 115 million by 2050. The annual costs are estimated to be €55B in Europe and €450B worldwide (1% of the World Gross Domestic Product). In 2012, the WHO declared dementia a global health priority, highlighting the urgent need for improvements in this area.

The consortium assembles highly recognised engineering, physical, biomedical and clinical scientists and industrial partners from across Europe. We will deliver the first patient-specific predictive models for early differential diagnosis of dementias and their evolution. An integrated clinical decision-support platform will be validated/ tested by access to a dozen databases of international studies.  This will be first integrative and validated multiscale modelling platform for biomedical research and clinical decision support.

Saturday, March 5, 13:30-15:30, Room Z
The VPH-DARE@IT Project: Delivering a clinical decision support platform for earlier dementia diagnosis

View the session flyer here.

Moderator: Zeike Taylor

VPH-DARE@IT: towards early, differential diagnosis of
Alejandro Frangi;Sheffield/UK

Clinical platform for data-driven differential diagnostics of
cognitive disorders
Mark van Gils; Tampere/FI

Shared research as a service platform for translating research into clinical practice for dementia (20′)
Susheel Varma; Sheffield/UK

In silico characterisation of white matter microstructure
using diffusion MRI
Leandro Beltrachini; Sheffield/UK

Fluid Transport in the Ageing Brain: An Integrative Modelling Approach(20′)
Yiannis Ventikos; London/UK

Phenomenological modelling and the RSS (20′)
Wiro J. Niessen; Rotterdam/NL

Discussion (10′)

For more information on VPH-DARE@IT, join the session and stop by the EIBIR booth at ECR 2016 near the main entrance, or visit the project’s website at www.vph-dare.eu.

This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration under grant agreement no FP7-ICT-2011-9-601055.